Blue rubber bleb nevus syndrome brbns or bean syndrome is a rare sporadic syndrome characterized by multifocal venous anomalies patients often have multiple soft blue skin lesions blueberry muffin syndrome associated with multiple bowel venous malformations which could lead to lower gastrointestinal bleeding. There is frequently a family history with autosomal dominant inheritance i e. However it was later made famous in 1958 by william bennett bean for which the disease has been termed bean syndrome later referenced as.
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